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  6. Thermo Scientific Chemicals Calpain Inhibitor II, 95+%

Thermo Scientific Chemicals Calpain Inhibitor II, 95+%

An inhibitor of calpains I and II

87.50 - 339.00

Chemische identificatiekenmerken

CAS 136632-32-1
Moleculaire formule C19H35N3O4S, C19H35N3O4S
Synoniem N-Ac-Leu-Leu-Methioninal; ALLM
Meer specificaties weergeven

Producten 2
Produktcode Merk Aantal Prijs Hoeveelheid en beschikbaarheid  
Produktcode Merk Aantal Prijs Hoeveelheid en beschikbaarheid  
15484869
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Thermo Scientific Chemicals
J62491.#0 		5 mg This item is currently unavailable or has been discontinued.
View the product page for possible alternatives.
 		N/A
15494869
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Thermo Scientific Chemicals
J62491.MB 		25 mg
339.00
25 mg
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Beschrijving

Beschrijving

ALLM (Calpain Inhibitor) is a cell-permeable, peptide aldehyde inhibitor of calpain I and calpain II. ALLM acts as a very potent inhibitor of cathepsin L and the strongest inhibitor of cathepsin B amongst the peptide aldehydes. This compound inhibits the processing of malaria aspartic hemoglobinases plasmepsins I and II in vitro. ALLM also inhibits other neutral cysteine proteases, and activation-induced programmed cell death. It restores defective immune responses in HIV+ donors. ALLM blocks nitric oxide production by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene. ALLM also acts as a weak inhibitor of proteasome.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specificatie

Chemische identificatiekenmerken

136632-32-1
C19H35N3O4S, C19H35N3O4S
N-Ac-Leu-Leu-Methioninal; ALLM

Specificatie

White
An inhibitor of calpains I and II
C19H35N3O4S, C19H35N3O4S
N-Ac-Leu-Leu-Methioninal; ALLM
Signal Transduction Reagent
RJWLAIMXRBDUMH-UHFFFAOYNA-N
2-acetamido-4-methyl-N-(3-methyl-1-{[4-(methylsulfanyl)-1-oxobutan-2-yl]carbamoyl}butyl)pentanamide
≥95%
-30°C to -10°C
136632-32-1
401.60g/mol
Soluble in ethanol at 20mg/ml
Powder
CSCCC(NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(C)=O)C=O
401.57
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SDS
Documentatie

Documentatie

Product Certifications

RUO – Research Use Only

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