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  6. Thermo Scientific Chemicals Calpain Inhibitor II, 95+%
  7. 15494869

Thermo Scientific Chemicals Calpain Inhibitor II, 95+%

An inhibitor of calpains I and II

Merk:  Thermo Scientific Chemicals J62491.MB

336.99 EUR valid until 2025-12-31
Use promo code "25339" to get your promotional price.

Aantal 25 mg

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Produktcode. 15494869

  • 339.00 / 25 mg

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Beschrijving

Beschrijving

ALLM (Calpain Inhibitor) is a cell-permeable, peptide aldehyde inhibitor of calpain I and calpain II. ALLM acts as a very potent inhibitor of cathepsin L and the strongest inhibitor of cathepsin B amongst the peptide aldehydes. This compound inhibits the processing of malaria aspartic hemoglobinases plasmepsins I and II in vitro. ALLM also inhibits other neutral cysteine proteases, and activation-induced programmed cell death. It restores defective immune responses in HIV+ donors. ALLM blocks nitric oxide production by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene. ALLM also acts as a weak inhibitor of proteasome.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY
Specificatie

Chemische identificatiekenmerken

136632-32-1
C19H35N3O4S, C19H35N3O4S
N-Ac-Leu-Leu-Methioninal; ALLM

Specificatie

25 mg
-30°C to -10°C
136632-32-1
401.60g/mol
Soluble in ethanol at 20mg/ml
Powder
RJWLAIMXRBDUMH-UHFFFAOYNA-N
2-acetamido-4-methyl-N-(3-methyl-1-{[4-(methylsulfanyl)-1-oxobutan-2-yl]carbamoyl}butyl)pentanamide
≥95%
White
An inhibitor of calpains I and II
C19H35N3O4S, C19H35N3O4S
N-Ac-Leu-Leu-Methioninal; ALLM
Signal Transduction Reagent
7693643
CSCCC(NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(C)=O)C=O
401.57
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