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YTHDF2 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Merk: Proteintech 24744-1-AP-20UL
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Beschrijving
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation. Also acts as a promoter of cap-independent mRNA translation following heat shock stress: upon stress, relocalizes to the nucleus and specifically binds mRNAs with some m6A methylation mark at their 5′-UTR, protecting demethylation of mRNAs by FTO, thereby promoting cap-independent mRNA translation.Specificatie
| YTHDF2 | |
| Polyclonal | |
| Unconjugated | |
| YTHDF2 | |
| CLL associated antigen KW 14, HGRG8, NY REN 2, YTH domain family protein 2, YTH domain family, member 2, YTHDF2 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 51441 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry, Immunoprecipitation, Immunofluorescence, Western Blot | |
| 0.25 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q9Y5A9 | |
| YTHDF2 | |
| YTHDF2 Fusion Protein Ag5922 | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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