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YAP1 Rabbit anti-Human, Mouse, Zebrafish, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
145.00 € - 410.00 €
Specifications
Antigen | YAP1 |
---|---|
Concentration | 0.3 mg/mL |
Applications | Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Flow Cytometry, Immunocytochemistry |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16821874
|
Proteintech
13584-1-AP-20UL |
20 μL |
145.00 €
20µL |
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16811874
|
Proteintech
13584-1-AP-150UL |
150 μL |
410.00 €
150µL |
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Description
This antibody is a rabbit polyclonal antibody. The calculated molecular weight of YAP1 is 54 kDa, but phosphorylated YAP1 is about 65 kDa.
YAP1 (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway. The Hippo signaling pathway plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene results in coloboma.Specifications
YAP1 | |
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Flow Cytometry, Immunocytochemistry | |
Unconjugated | |
Rabbit | |
Zebrafish, Human, Mouse | |
P46937, P46938, Q1L8J7 | |
10413, 22601, 561411 | |
YAP1 Fusion Protein Ag4510 | |
Primary | |
-20°C | |
YAP1 |
0.3 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
65 kDa Yes associated protein, YAP, YAP1, YAP2, YAP65, YKI, Yorkie homolog | |
yap1 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |
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