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YAP1 Rabbit anti-Human, Mouse, Zebrafish, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00 € - 410.00 €

Specifications

Antigen YAP1
Concentration 0.3 mg/mL
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Flow Cytometry, Immunocytochemistry
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16821874
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Proteintech
13584-1-AP-20UL
20 μL
145.00 €
20µL
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16811874
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Proteintech
13584-1-AP-150UL
150 μL
410.00 €
150µL
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Description

Description

This antibody is a rabbit polyclonal antibody. The calculated molecular weight of YAP1 is 54 kDa, but phosphorylated YAP1 is about 65 kDa.

YAP1 (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway. The Hippo signaling pathway plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene results in coloboma.
Specifications

Specifications

YAP1
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Flow Cytometry, Immunocytochemistry
Unconjugated
Rabbit
Zebrafish, Human, Mouse
P46937, P46938, Q1L8J7
10413, 22601, 561411
YAP1 Fusion Protein Ag4510
Primary
-20°C
YAP1
0.3 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
65 kDa Yes associated protein, YAP, YAP1, YAP2, YAP65, YKI, Yorkie homolog
yap1
IgG
Antigen Affinity Chromatography
Antibody
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