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tert-Butyldimethylchlorosilane, 97%, Thermo Scientific Chemicals

CAS: 18162-48-6 | C6H15ClSi | 150.721 g/mol

33.57 - 381.90

Chemische identificatiekenmerken

CAS 18162-48-6
Moleculaire formule C6H15ClSi
Molecular Weight (g/mol) 150.721
MDL-nummer MFCD00000501
InChI Key BCNZYOJHNLTNEZ-UHFFFAOYSA-N
Synoniem tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride
PubChem CID 28928
ChEBI CHEBI:85071
IUPAC Name tert-butyl-chloro-dimethylsilane
SMILES CC(C)(C)[Si](C)(C)Cl
Meer specificaties weergeven

Producten 3
Produktcode Merk Aantal Prijs Hoeveelheid en beschikbaarheid  
Produktcode Merk Aantal Prijs Hoeveelheid en beschikbaarheid  
11474364
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Thermo Scientific Alfa Aesar
A13064.06
5 g
33.57
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11484364
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Thermo Scientific Alfa Aesar
A13064.14
25 g
142.71
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11494364
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Thermo Scientific Alfa Aesar
A13064.22
100 g
381.90
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Beschrijving

Beschrijving

tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.

Solubility
Soluble in chloroform and ethyl acetate. Insoluble in water.

Notes
Moisture sensitive. Store in cool place. Incompatible with bases, metals, oxidizing agents and alcohols.
Specificatie

Chemische identificatiekenmerken

18162-48-6
150.721
BCNZYOJHNLTNEZ-UHFFFAOYSA-N
28928
tert-butyl-chloro-dimethylsilane
C6H15ClSi
MFCD00000501
tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride
CHEBI:85071
CC(C)(C)[Si](C)(C)Cl

Specificatie

124°C to 126°C
86°C to 89°C
C6H15ClSi
MFCD00000501
505999
tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride
BCNZYOJHNLTNEZ-UHFFFAOYSA-N
tert-butyl-chloro-dimethylsilane
28928
150.73
Pungent
0.81
tert-Butyldimethylchlorosilane
18162-48-6
(CH3)3CSi(CH3)2Cl
UN2925
22°C (72°F)
Soluble in chloroform and ethyl acetate. Insoluble in water.
CC(C)(C)[Si](C)(C)Cl
150.721
CHEBI:85071
97%
Moisture sensitive
Video's
Veiligheid en behandeling

Veiligheid en behandeling

GHS H Statement
H228-H314-H318
Flammable solid.
Causes severe skin burns and eye damage.
Causes serious eye damage.

P210-P240-P241-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c

H228-H314-H335

missing translation for 'dotInformation' : Hazard Class: 8; Packaging Group: I

missing translation for 'einecsNumber' : 242-042-4

missing translation for 'rtecsNumber' : VV2000000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Productidentificatie
  • tert-Butyldimethylchlorosilane

Signaalwoord
  • Gevaar

Gevarencategorie
  • AQUATISCH GEVAAR OP LANGE TERMIJN Categorie 2 voor chronische toxiciteit
  • Ernstig oogletsel/oogirritatie Categorie 1
  • Ontvlambare vaste stof Categorie 2
  • Huidcorrosie/-irritatie Indeling Categorie 1A

Gevarenaanduiding
  • H228-Ontvlambare vaste stof.
  • H314-Veroorzaakt ernstige brandwonden en oogletsel.
  • H318-Veroorzaakt ernstig oogletsel.
  • H411-Giftig voor in het water levende organismen, met langdurige gevolgen.

Veiligheidsmaatregel
  • P210-Verwijderd houden van warmte, hete oppervlakken, vonken, open vuur en andere ontstekingsbronnen. Niet roken.
  • P280-Beschermende handschoenen/beschermende kleding/oog­bescherming/gelaatsbescherming dragen.
  • P301+P330+P331-NA INSLIKKEN: de mond spoelen - GEEN braken opwekken.
  • P303+P361+P353-BIJ CONTACT MET DE HUID (of het haar): verontreinigde kleding onmiddellijk uittrekken. Huid met water afspoelen/afdouchen.
  • P305+P351+P338-BIJ CONTACT MET DE OGEN: voorzichtig afspoelen met water gedurende een aantal minuten; contactlenzen verwijderen, indien mogelijk; blijven spoelen.
  • P310-Onmiddellijk een ANTIGIFCENTRUM/arts/ raadplegen.

Aanvullende informatie
  • MIXTURE LIST-Bevat: Chloro(1,1-dimethylethyl)dimethyl-silane

SDS
Documentatie

Documentatie

Product Certifications

RUO – Research Use Only

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