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  6. Staurosporine, 99+%, Thermo Scientific Chemicals

Staurosporine, 99+%, Thermo Scientific Chemicals

Staurosporine (staurosporin, CAS # 62996-74-1) is a bacterial alkyloid isolated from Streptomyces staurosporeus.

125.42 - 752.75

Chemische identificatiekenmerken

CAS 62996-74-1
Moleculaire formule C28H26N4O3
Molecular Weight (g/mol) 466.541
MDL-nummer MFCD00077402
InChI Key HKSZLNNOFSGOKW-ZYSRIHRCSA-N
Synoniem Antibiotic AM-2282
PubChem CID 49831000
SMILES CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
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Producten 3
Produktcode Merk Aantal Prijs Hoeveelheid en beschikbaarheid  
Produktcode Merk Aantal Prijs Hoeveelheid en beschikbaarheid  
15495139
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Thermo Scientific Alfa Aesar
J62837.M^ 		1 mg
125.42
1 mg
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15485139
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Thermo Scientific Alfa Aesar
J62837.#0 		5 mg
412.05
5 mg
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15405149
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Thermo Scientific Alfa Aesar
J62837.MA 		10 mg
752.75
10 mg
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Beschrijving

Beschrijving

Broad spectrum protein kinase inhibitor Staurosporine is used as anti-fungal and anti-hypertensive, which results to study the anti-cancer treatment. It acts as a precursor to protein kinase inhibitor midostaurin. It is also used to induce cell death in Swiss Webster primary macrophage cells and to study the effect of caspase activation on human sperm quality.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Staurosporine is an indolocarbazole alkaloid capable of permeating cell membranes
  • Staurosporine has anti-cancer properties that can induce apoptosis
  • Staurosporine is a broad inhibitor of protein kinases, preventing growth and division cycles

Application

  • Staurosporine is used for research on acute myeloid leukemia
  • It is suitable for research applications including cell culture and biochemistry
Specificatie

Chemische identificatiekenmerken

62996-74-1
466.541
HKSZLNNOFSGOKW-ZYSRIHRCSA-N
49831000
C28H26N4O3
MFCD00077402
Antibiotic AM-2282
CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC

Specificatie

Staurosporine
Powder
240°C to 243°C
C28H26N4O3
1060573
Antibiotic AM-2282
HKSZLNNOFSGOKW-ZYSRIHRCSA-N
466.541
466.54
Staurosporine
62996-74-1
Yellow
MFCD00077402
14,8802
Soluble in DMSO or ethanol;Soluble in dimethyl sulfoxide ,dimethyl formamide,ethyl acetate,hot acetone and ethanol; Slightly soluble in chloroform and methanol; Insoluble in water.
CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
49831000
≥99%
Video's
Veiligheid en behandeling

Veiligheid en behandeling

GHS H Statement
H350
May cause cancer.

P201-P202-P280-P308+P313-P501c

H351

missing translation for 'rtecsNumber' : KD5084000

missing translation for 'tsca' : No

missing translation for 'storageNote' : -30° to -10°C

Recommended Storage : Store at -20°C

Productidentificatie
  • Staurosporine

Signaalwoord
  • Waarschuwing

Gevarencategorie
  • Kankerverwekkendheid Categorie 2

Gevarenaanduiding
  • H351-Verdacht van het veroorzaken van kanker.

Veiligheidsmaatregel
  • P201-Alvorens te gebruiken de speciale aanwijzingen raadplegen.
  • P280-Beschermende handschoenen/beschermende kleding/oog­bescherming/gelaatsbescherming dragen.
  • P308+P313-NA (mogelijke) blootstelling: een arts raadplegen.

SDS
Documentatie

Documentatie

Product Certifications

RUO – Research Use Only

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