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SPDEF Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00 - 410.00

Specificatie

Antigeen SPDEF
Concentratie 0.31 mg/mL
Toepassingen Western Blot
Classificatie Polyclonal
Conjugaat Unconjugated
Meer specificaties weergeven

Producten 2
Produktcode Merk Aantal Prijs Hoeveelheid en beschikbaarheid  
Produktcode Merk Aantal Prijs Hoeveelheid en beschikbaarheid  
16898563
Bekijk documenten
Proteintech
11467-1-AP-20UL
20 μL
145.00
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16888563
Bekijk documenten
Proteintech
11467-1-AP-150UL
150 μL
410.00
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Beschrijving

Beschrijving

PDEF (prostate-derived Ets factor) is a 37.5- kDa protein that acts as an androgen-independent transcriptional activator for the PSA (prostate specific antigen) promoter. It also interacts directly with the DNA binding domain of androgen receptor and enhances androgen-mediated activation of the PSA promoter. PDEF was shown to have transcript levels 192-fold higher in the peripheral blood of some breast cancer patients in comparison with normal individuals. PDEF mRNA is also frequently over-expressed in human breast tumors as well as in human ovarian tumors. In ovarian tumors, PDEF expression seems to down-modulate maligt potential, and thus provides a rationale to screen for drugs that induce PDEF expression in epithelial ovarian tumors.
Specificatie

Specificatie

SPDEF
Western Blot
Unconjugated
Rabbit
Mouse, Rat, Human
O95238, Q9WTP3
25803, 30051, 689210
SPDEF Fusion Protein Ag2020
Primary
-20°C
SPDEF
0.31 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
PDEF, Prostate derived Ets factor, Prostate specific Ets, PSE, RP11 375E1__A.3, SPDEF
SPDEF
IgG
Antigen Affinity Chromatography
Antibody
Video's
SDS
Documentatie

Documentatie

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