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SOX10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Merk: Proteintech 10422-1-AP-20UL
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Beschrijving
SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. SOX10 plays a central role in developing and maturing of glia. Specifically, SOX10 activates expression of myelin genes (such as DUSPP15 and MYRF) during oligodendrocyte (OL) maturation; thus, playing a central role in oligodendrocyte maturation and CNS myelination. Once induced MYRF cooperates with SOX10 to implement the myelination program. SOX10 is also a transcriptional activator of MITF acting synergistically with PAX3. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.Specificatie
| SOX10 | |
| Polyclonal | |
| Unconjugated | |
| SOX10 | |
| DOM, SOX10, Transcription factor SOX 10, WS2E, WS4 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 20665, 29361, 6663 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 0.4 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| O55170, P56693, Q04888 | |
| SOX10 | |
| SOX10 Fusion Protein Ag0673 | |
| 20 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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