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Prednisone, 98%, Thermo Scientific Chemicals
Prednisone, 98%, CAS # 53-03-2, is a synthetic glucocorticoid with anti-inflammatory, immunomodulatory, antineoplastic, and adrenergic activities.
171.86 - 595.97
Chemische identificatiekenmerken
| CAS | 53-03-2 |
|---|---|
| Moleculaire formule | C21H26O5 |
| Molecular Weight (g/mol) | 358.434 |
| InChI Key | XOFYZVNMUHMLCC-ZPOLXVRWSA-N |
| Synoniem | prednisone, deltasone, dehydrocortisone, decortin, meticorten, orasone, prednison, rectodelt, ultracorten, dacortin |
| PubChem CID | 5865 |
| ChEBI | CHEBI:8382 |
| IUPAC Name | (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione |
| SMILES | CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C |
| Produktcode | Merk | Aantal | Verpakking | Prijs | Hoeveelheid en beschikbaarheid | ||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Merk | Aantal | Verpakking | Prijs | Hoeveelheid en beschikbaarheid | ||||
|
13458638
|
Thermo Scientific Acros
448950050 |
5 g | Glass bottle |
171.86
5 gram |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | ||||
|
13468638
|
Thermo Scientific Acros
448950250 |
25 g | Glass Bottle |
595.97
25 gram |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | ||||
Beschrijving
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities
• It shows antineoplastic and adrenergic activities against hormone-sensitive cancer cells
• This compound binds to its receptors and enters the nucleus activating specific nuclear receptors, resulting in an altered gene expression and inhibiting proinflammatory cytokine production
Applications
• Prednisone can reduce circulating lymphocytes, promote cell differentiation, and stimulate apoptosis in sensitive tumor cell lines
• It is considered a prodrug that is converted by the liver into prednisolone which is the active steroid compound
• It is also used in some studies to investigate the effects of daily administration of MIDD0301, on the animal and organs weights and hematological profile
Chemische identificatiekenmerken
| 53-03-2 | |
| 358.434 | |
| prednisone, deltasone, dehydrocortisone, decortin, meticorten, orasone, prednison, rectodelt, ultracorten, dacortin | |
| CHEBI:8382 | |
| CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C |
| C21H26O5 | |
| XOFYZVNMUHMLCC-ZPOLXVRWSA-N | |
| 5865 | |
| (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione |
Specificatie
| Prednisone | |
| 98% | |
| prednisone, deltasone, dehydrocortisone, decortin, meticorten, orasone, prednison, rectodelt, ultracorten, dacortin | |
| CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C | |
| 358.434 | |
| CHEBI:8382 |
| 53-03-2 | |
| C21H26O5 | |
| XOFYZVNMUHMLCC-ZPOLXVRWSA-N | |
| (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione | |
| 5865 | |
| 358.43 |
Veiligheid en behandeling
Productidentificatie
Signaalwoord
Gevarencategorie
Gevarenaanduiding
Veiligheidsmaatregel
- Prednisone
Signaalwoord
- Waarschuwing
Gevarencategorie
- Giftigheid voor de voortplanting Categorie 2
Gevarenaanduiding
- H361-Kan mogelijks de vruchtbaarheid of het ongeboren kind schaden.
Veiligheidsmaatregel
- P201-Alvorens te gebruiken de speciale aanwijzingen raadplegen.
- P202-Pas gebruiken nadat u alle veiligheidsvoorschriften gelezen en begrepen heeft.
- P280-Beschermende handschoenen/beschermende kleding/oogbescherming/gelaatsbescherming dragen.
- P308+P313-NA (mogelijke) blootstelling: een arts raadplegen.
RUO – Research Use Only
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