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NCAM1/CD56 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Merk:  Proteintech 14255-1-AP-150UL

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Produktcode. 16882814

  • 410.00 / 150 µL

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Beschrijving

Beschrijving

NCAM, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig)-like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins.
Specificatie

Specificatie

NCAM1/CD56
Polyclonal
Unconjugated
NCAM1
CD56, MSK39, N CAM 1, NCAM, NCAM 1, NCAM1
Rabbit
Antigen Affinity Chromatography
RUO
17967, 24586, 4684
-20°C
Liquid
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
0.27 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P13591, P13595, P13596
Ncam1
NCAM1/CD56 Fusion Protein Ag5528
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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