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Thermo Scientific Chemicals Mitomycin C, contains 2 mg Mitomycin C and 48 mg NaCl

Mitomycin C, CAS # 50-07-7, is a methylazirinopyrroloindoledione complex isolated from the bacterium Streptomyces caespitosus and other Streptomyces bacterial species. It is a versatile and potent compound with antibiotic activity and may have potential therapeutic value in the treatment of cancer. | CAS: 50-07-7 | C15H18N4O5 | 334.32 g/mol

Merk:  Thermo Scientific Chemicals 226940020

133.00 EUR valid until 2025-12-31
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Produktcode. 10286710

  • 138.00 /

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Beschrijving

Beschrijving

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

  • Mitomycin C is a water soluble, blue-violet crystalline powder, unstable in light and acidic conditions, but may be stably stored at 2-8°c
  • Bio-reduced mitomycin C generates oxygen radicals, alkylates DNA, and produces inter-strand DNA cross-links, thereby inhibiting DNA synthesis

Applications

  • Mitomycin C is preferentially toxic to hypoxic cells that are resistant to cancer therapy, and is therefore used to study its potential therapeutic effect on advanced stages of cancer
  • At high concentrations, mitomycin C inhibits RNA and protein synthesis and demonstrates strong antibiotic properties towards both Gram-positive and Gram-negative bacteria
TRUSTED_SUSTAINABILITY
Specificatie

Specificatie

Mitomycin C
>360.0°C
Ampoule
MFCD00078109
15, 6300
Solubility in water: soluble. Other solubilities: soluble in methanol, acetone, butyl acetate and, cyclohexanone;, slightly soluble in benzene, ccl4, diethyl ether;, practically insoluble in petroleum ether.
CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N
5746
334.32
Powder
50-07-7, 7647-14-5
Blue-Violet
C15H18N4O5
2 mg
mitomycin c, mitomycin, ametycine, mutamycin, ametycin, mitocin-c, mitomycinum, mytomycin, mytozytrex, mitomycin-c
NWIBSHFKIJFRCO-WUDYKRTCSA-N
334.32
CHEBI:27504
≥99% with regard to the non-formulated material
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Productidentificatie
  • Mitomycin C

Signaalwoord
  • Waarschuwing

Gevarencategorie
  • Acute toxiciteit Categorie 4
  • Kankerverwekkendheid Categorie 2

Gevarenaanduiding
  • H351-Verdacht van het veroorzaken van kanker.
  • H302-Schadelijk bij inslikken.

Veiligheidsmaatregel
  • P280-Beschermende handschoenen/beschermende kleding/oog­bescherming/gelaatsbescherming dragen.
  • P301+P312-NA INSLIKKEN: bij onwel voelen een ANTIGIFCENTRUM / arts/ raadplegen.

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