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Melanophilin Mouse anti-Human, Porcine, Clone: 1A8D12, Proteintech
Mouse Monoclonal Antibody
Merk: Proteintech 66092-1-IG-20UL
This item is not returnable.
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Beschrijving
Slac2-a (for synaptotagmin-like protein (Slp) homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes. Slac2-a binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its synaptotagmin-like protein homology domain (SHD), which is located near the N-terminus. The transport of pigment and cytotoxic granules in melanocytes requires the stable formation of this complex, and thus mutations in the binding domains of the three protein components may cause albinism and/or severe immune disorders.Specificatie
| Melanophilin | |
| Monoclonal | |
| 0.77 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q9BV36 | |
| MLPH | |
| Melanophilin Fusion Protein Ag19286 | |
| 20 μL | |
| Primary | |
| Pig, Human | |
| Antibody | |
| IgG1 |
| Immunofluorescence, Immunocytochemistry, Western Blot, Immunohistochemistry (Paraffin) | |
| 1A8D12 | |
| Unconjugated | |
| MLPH | |
| Exophilin 3, melanophilin, MLPH, SLAC2 A, SLAC2A, Synaptotagmin like protein 2a | |
| Mouse | |
| Protein G | |
| RUO | |
| 100049680, 79083 | |
| -20°C | |
| Liquid |
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