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  6. Deoxycholic acid, sodium salt, 99%, extra pure, Thermo Scientific Chemicals

Deoxycholic acid, sodium salt, 99%, extra pure, Thermo Scientific Chemicals

Deoxycholic acid, sodium salt, CAS # 302-95-4, also designed as sodium deoxycholate, is a biological anionic bile acid detergent that is especially useful for disrupting and dissociating protein interactions.

50.50 - 324.00

Chemische identificatiekenmerken

CAS 302-95-4
Moleculaire formule C24H39NaO4
Molecular Weight (g/mol) 414.56
MDL-nummer MFCD00064139
InChI Key FHHPUSMSKHSNKW-SMOYURAASA-M
Synoniem sodium deoxycholate
PubChem CID 91810855
SMILES [Na+].[H][C@@]12CC[C@H]([C@H](C)CCC([O-])=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C
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Producten 3
Produktcode Merk Aantal Verpakking Prijs Hoeveelheid en beschikbaarheid  
Produktcode Merk Aantal Verpakking Prijs Hoeveelheid en beschikbaarheid  
10104560
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Thermo Scientific Acros
218590250 		25 g Glass bottle
50.50
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10732451
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Thermo Scientific Acros
218591000 		100 g Glass bottle
99.65
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10562904
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Thermo Scientific Acros
218595000 		500 g Glass bottle
324.00
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Beschrijving

Beschrijving

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • The deoxycholic acid sodium salt is a bile acid choleretic and anionic detergent that allows the solubilization of fats for intestinal absorption
  • The compound is an intermediate in the production of corticosteroids
  • In animal models it has been shown that this compound can promote tyrosine phosphorylation of β-catenin and its translocation to the nucleus, promoting the activation of β-catenin signaling


Applications

  • Deoxycholic acid is mainly useful for the extraction of membrane receptors, other plasma membrane proteins, nuclei isolation, solubilization and isolation of fats, and some components of biological membranes (in an active state)
  • It has been used for chemical applications, mainly for the elution or regeneration of specific types of affinity columns. Furthermore, this compound can be used to prevent non-specific binding in affinity chromatography.
  • It has been applied in the preparation of protein extracts for immunoblotting and immunoprecipitation of radiolabeled proteins
  • Deoxycholic acid, sodium salt is also recommended for stripping endotoxins
Specificatie

Chemische identificatiekenmerken

302-95-4
414.56
FHHPUSMSKHSNKW-SMOYURAASA-M
91810855
C24H39NaO4
MFCD00064139
sodium deoxycholate
[Na+].[H][C@@]12CC[C@H]([C@H](C)CCC([O-])=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C

Specificatie

Deoxycholic acid, sodium salt
White to Cream
5% max. (2 g, 105°C, 4 hrs)
99%
MFCD00064139
14, 2899
sodium deoxycholate
[Na+].[H][C@@]12CC[C@H]([C@H](C)CCC([O-])=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C
414.56
414.58
Extra Pure
302-95-4
7.5 to 10 (5% aq. soln.)
Authentic
C24H39NaO4
10, III, 1642
+42° to +46° (20°C, 589nm) (c=2, water)
FHHPUSMSKHSNKW-SMOYURAASA-M
sodium;(4R)-4-[(3R,5R,8R,10S,12S,13R,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
91810855
98.5 to 102% (on dry substance)
Crystalline Powder
Video's
Veiligheid en behandeling

Veiligheid en behandeling

GHS H Statement:
Harmful if swallowed.
May cause respiratory irritation.

GHS P Statement:
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

Productidentificatie
  • Deoxycholic acid, sodium salt

Signaalwoord
  • Waarschuwing

Gevarencategorie
  • Acute toxiciteit Categorie 4
  • Dzia anie toksyczne na narzady docelowe Categorie 3

Gevarenaanduiding
  • H335-Kan irritatie van de luchtwegen veroorzaken.
  • H302-Schadelijk bij inslikken.

Veiligheidsmaatregel
  • P261-Inademing van stof/rook/gas/nevel/damp/spuitnevel vermijden.
  • P264-Na het werken met dit product grondig wassen.
  • P304+P340-NA INADEMING: de persoon in de frisse lucht brengen en ervoor zorgen dat deze gemakkelijk kan ademen.
  • P312-Bij onwel voelen een ANTIGIFCENTRUM/arts/ raadplegen.

SDS
Documentatie

Documentatie

Product Certifications

RUO – Research Use Only

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