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MTHFD2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Merk:  Invitrogen PA530407

Produktcode. 13404907

  • 522.00 /

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Beschrijving

Beschrijving

Recommended positive controls: A549, HeLa, HepG2, HCT116. Predicted reactivity: Mouse (96%), Rat (95%), Zebrafish (85%), Xenopus laevis (89%), Chicken (85%), Bovine (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
TRUSTED_SUSTAINABILITY
Specificatie

Specificatie

MTHFD2
Polyclonal
Unconjugated
MTHFD2
AW558851; Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; Methenyltetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase 2; Mthfd2; NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase; NAD-dependent methylenetetrahydrofolate dehydrogenase; NMDMC
Rabbit
Antigen affinity chromatography
RUO
10797, 17768, 680308
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
0.61 mg/mL
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
P13995, P18155
MTHFD2
Recombinant fragment corresponding to a region within amino acids 141 and 350 of Human MTHFD2
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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