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Transferrin Receptor Monoclonal Antibody (R17217.1.4), FITC, Invitrogen™

Rat Monoclonal Antibody

Merk:  Invitrogen MA517922

Produktcode. 15304201

  • 540.00 /

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Beschrijving

Beschrijving

MA5-17922 targets CD71/transferrin receptor in FACS applications and shows reactivity with Mouse samples.

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
TRUSTED_SUSTAINABILITY
Specificatie

Specificatie

Transferrin Receptor
Monoclonal
0.1 mg/mL
PBS with 4-5mg/mL BSA and 0.02% sodium azide
Q62351
TFRC
Friend erythroleukemia 745.6 induced for 5 days in 1.5% dimethyl sulfoxide.
300 μg
Primary
Mouse
Antibody
IgG2a
Flow Cytometry
R17217.1.4
FITC
TFRC
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Rat
Protein G
RUO
22042
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Liquid
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