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Ampicillin, Thermo Scientific Chemicals
Ampicillin, CAS # 69-53-4, is structurally related to penicillin and is considered to be a semi-synthetic antibiotic with antibacterial activity.
180.00 - 459.00
Chemische identificatiekenmerken
| CAS | 69-53-4 |
|---|---|
| Moleculaire formule | C16H19N3O4S |
| Molecular Weight (g/mol) | 349.405 |
| MDL-nummer | MFCD00005175 |
| InChI Key | AVKUERGKIZMTKX-NJBDSQKTSA-N |
| PubChem CID | 6249 |
| ChEBI | CHEBI:28971 |
| IUPAC Name | (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| SMILES | CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C |
| Produktcode | Merk | Aantal | Prijs | Hoeveelheid en beschikbaarheid | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Merk | Aantal | Prijs | Hoeveelheid en beschikbaarheid | |||||
|
15493649
|
Thermo Scientific Alfa Aesar
J60977.06 |
5 g |
180.00
5 gram |
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|
15403659
|
Thermo Scientific Alfa Aesar
J60977.14 |
25 g |
459.00
25 gram |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Beschrijving
Ampicillin is used as asemi-synthetic antibiotic which has antibacterial activity structurally related to penicillin. It is widely used selection reagent for transformed cells expressing β-lactamase. It is also used to prevent and treat a number of bacterial infections. It may also be used to prevent group B streptococcal infection in newborns.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Ampicillin is a broad-spectrum, semi-synthetic, β-lactam penicillin with bactericidal activity. It acts against several gram-positive and -negative infections
- This compound binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. This inactivation interferes with the cross-linkage of peptidoglycan chains essential for bacterial cell wall strength and rigidity. Consequently, there is an interruption in the bacterial cell wall synthesis which results in the weakening of the bacterial cell wall causing cell lysis
Application
- In laboratory experiments, it is commonly used as a selector reagent for transformed cells expressing β-lactamase. The ampicillin-resistant gene (ampR) catalyzes the hydrolysis of the β-lactam ring of ampicillin and naturally detoxifies the drug
- Ampicillin is commonly used as a selection marker for E. coli and other bacteria during plasmid DNA isolation, protein expression, and gene cloning
Chemische identificatiekenmerken
| 69-53-4 | |
| 349.405 | |
| AVKUERGKIZMTKX-NJBDSQKTSA-N | |
| CHEBI:28971 | |
| CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C |
| C16H19N3O4S | |
| MFCD00005175 | |
| 6249 | |
| (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
Specificatie
| Ampicillin | |
| Powder | |
| 208°C (decomposition) | |
| C16H19N3O4S | |
| 1090925 | |
| In 1 M NH4OH,50mg/ml | |
| CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C | |
| 349.405 | |
| CHEBI:28971 |
| Ampicillin | |
| 69-53-4 | |
| White | |
| MFCD00005175 | |
| 14,586 | |
| AVKUERGKIZMTKX-NJBDSQKTSA-N | |
| (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid | |
| 6249 | |
| 349.4 |
Veiligheid en behandeling
GHS H Statement
H334-H335-H315-H319-H317
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause respiratory irritation.
Causes skin irritation.
Causes serious eye irritation.
May cause an allergic skin reaction.
P261-P264b-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P333+P313-P342+P311-P362-P501c
H315-H317-H319-H334-H335
missing translation for 'einecsNumber' : 200-709-7
missing translation for 'rtecsNumber' : XH8350000
missing translation for 'tsca' : No
Recommended Storage : Keep cold
Productidentificatie
Signaalwoord
Gevarencategorie
Gevarenaanduiding
Veiligheidsmaatregel
Aanvullende informatie
- Ampicillin
Signaalwoord
- Gevaar
Gevarencategorie
- Ernstig oogletsel/oogirritatie Categorie 2
- Sensibilisatie van de luchtwegen Categorie 1
- Huidcorrosie/-irritatie Indeling Categorie 2
- Sensibilisering van de huid Categorie 1
- Dzia anie toksyczne na narzady docelowe Categorie 3
Gevarenaanduiding
- H315-Veroorzaakt huidirritatie.
- H317-Kan een allergische huidreactie veroorzaken.
- H319-Veroorzaakt ernstige oogirritatie.
- H334-Kan bij inademing allergie- of astmasymptomen of ademhalingsmoeilijkheden veroorzaken.
- H335-Kan irritatie van de luchtwegen veroorzaken.
Veiligheidsmaatregel
- P280-Beschermende handschoenen/beschermende kleding/oogbescherming/gelaatsbescherming dragen.
- P302+P352-BIJ CONTACT MET DE HUID: met veel water/ wassen.
- P304+P340-NA INADEMING: de persoon in de frisse lucht brengen en ervoor zorgen dat deze gemakkelijk kan ademen.
- P312-Bij onwel voelen een ANTIGIFCENTRUM/arts/ raadplegen.
- P332+P313-Bij huidirritatie: een arts raadplegen.
- P333+P313-Bij huidirritatie of uitslag: een arts raadplegen.
- P337+P313-Bij aanhoudende oogirritatie: een arts raadplegen.
Aanvullende informatie
- MIXTURE LIST-Bevat: Ampicillin
RUO – Research Use Only
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