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A23187, 98%, free acid, Thermo Scientific Chemicals
A23187 (Calcimycin), CAS # 52665-69-7, is a calcium ionophore-based antibiotic.
51.95 - 169.00
Chemische identificatiekenmerken
| CAS | 52665-69-7 |
|---|---|
| Moleculaire formule | C29H37N3O6 |
| Molecular Weight (g/mol) | 523.63 |
| MDL-nummer | MFCD00151202,MFCD00151202 |
| InChI Key | HIYAVKIYRIFSCZ-CVXKHCKVSA-N |
| PubChem CID | 97043288 |
| IUPAC Name | 5-(methylamino)-2-[[(2R,3S,5S,6S,8S,9S)-3,5,9-trimethyl-2-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylic acid |
| SMILES | CNC1=CC=C2OC(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)C3=CC=CN3)[C@H](C)C[C@H]4C)=NC2=C1C(O)=O |
| Produktcode | Merk | Aantal | Verpakking | Prijs | Hoeveelheid en beschikbaarheid | ||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Merk | Aantal | Verpakking | Prijs | Hoeveelheid en beschikbaarheid | ||||
|
10397811
|
Thermo Scientific Acros
328080010 |
1 mg | Glass Bottle in Plastic Container |
51.95
|
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
10036163
|
Thermo Scientific Acros
328080050 |
5 mg | Glass Bottle |
169.00
|
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Beschrijving
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
• A23187 is a polyether substance that permeabilizes cell membranes to calcium and other divalent cations
Applications
• A23187 can be used for the study of mitochondrial physiology because it acts as an uncoupling agent
• A23187 can be used to study the roles of divalent cations in cell physiology
• When bound to fluorescent calcium ions, A23187 can be useful for imaging studies
Chemische identificatiekenmerken
| 52665-69-7 | |
| 523.63 | |
| HIYAVKIYRIFSCZ-CVXKHCKVSA-N | |
| 5-(methylamino)-2-[[(2R,3S,5S,6S,8S,9S)-3,5,9-trimethyl-2-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylic acid |
| C29H37N3O6 | |
| MFCD00151202,MFCD00151202 | |
| 97043288 | |
| CNC1=CC=C2OC(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)C3=CC=CN3)[C@H](C)C[C@H]4C)=NC2=C1C(O)=O |
Specificatie
| A23187 | |
| Solid | |
| 97.5 | |
| 182.0°C to 193.0°C | |
| White | |
| C29H37N3O6 | |
| 15, 1642 | |
| HIYAVKIYRIFSCZ-CVXKHCKVSA-N | |
| 5-(methylamino)-2-[[(2R,3S,5S,6S,8S,9S)-3,5,9-trimethyl-2-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylic acid | |
| 97043288 | |
| 98% |
| Free acid | |
| 52665-69-7 | |
| 100.0 | |
| Authentic | |
| 98% | |
| MFCD00151202,MFCD00151202 | |
| Solubility in water: .. Other solubilities: soluble in dmso, ethylacetate, methanol, ethanol | |
| CNC1=CC=C2OC(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)C3=CC=CN3)[C@H](C)C[C@H]4C)=NC2=C1C(O)=O | |
| 523.63 | |
| 523.63 |
Veiligheid en behandeling
GHS H Statement:
Harmful in contact with skin.
Harmful if inhaled.
May cause respiratory irritation.
Causes skin irritation.
Harmful if swallowed.
Causes serious eye irritation.
GHS P Statement:
IF ON SKIN: Wash with plenty of soap and water.
Wear protective gloves/protective clothing/eye protection/face protection.
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.
GHS Signal Word: Warning
Productidentificatie
Signaalwoord
Gevarencategorie
Gevarenaanduiding
Veiligheidsmaatregel
- A23187 (free acid)
Signaalwoord
- Waarschuwing
Gevarencategorie
- Acute toxiciteit Categorie 4
- Ernstig oogletsel/oogirritatie Categorie 2
- Huidcorrosie/-irritatie Indeling Categorie 2
- Dzia anie toksyczne na narzady docelowe Categorie 3
Gevarenaanduiding
- H315-Veroorzaakt huidirritatie.
- H319-Veroorzaakt ernstige oogirritatie.
- H335-Kan irritatie van de luchtwegen veroorzaken.
- H312-Schadelijk bij contact met de huid.
- H332-Schadelijk bij inademing.
- H302-Schadelijk bij inslikken.
Veiligheidsmaatregel
- P261-Inademing van stof/rook/gas/nevel/damp/spuitnevel vermijden.
- P280-Beschermende handschoenen/beschermende kleding/oogbescherming/gelaatsbescherming dragen.
- P301+P312-NA INSLIKKEN: bij onwel voelen een ANTIGIFCENTRUM / arts/ raadplegen.
- P302+P352-BIJ CONTACT MET DE HUID: met veel water/ wassen.
- P304+P340-NA INADEMING: de persoon in de frisse lucht brengen en ervoor zorgen dat deze gemakkelijk kan ademen.
- P305+P351+P338-BIJ CONTACT MET DE OGEN: voorzichtig afspoelen met water gedurende een aantal minuten; contactlenzen verwijderen, indien mogelijk; blijven spoelen.
RUO – Research Use Only
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