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  7. 15781819

Thermo Scientific™ Pierce™ EDC-crosslinker

Immobilize or conjugate proteins using 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (CAS 25952-53-8), a water-soluble, carboxyl-to-amine crosslinker.

Merk:  Thermo Scientific™ A35391

164.35 EUR valid until 2025-05-31
Use promo code "25977" to get your promotional price.


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Beschrijving

Beschrijving

Thermo Scientific™ Pierce EDC is a water-soluble carbodiimide crosslinker that activates carboxyl groups for spontaneous reaction with primary amines, enabling peptide immobilization and hapten-carrier protein conjugation.

Thermo Scientific No-Weigh products are specialty reagents provided in pre-aliquoted format. The pre-weighed packaging helps prevent loss of reagent reactivity and contamination over time by minimizing repetitive opening and closing of vial. The format enables use of fresh vial of reagent each time, eliminating hassle of weighing small amounts of reagents and reducing concerns over reagent stability.

  • Reactive group: Carbodiimide
  • Reaction target: Activates carboxyl groups to conjugate to amino groups (primary amines)
  • Several conjugation strategies: React EDC alone with target groups or include NHS or Sulfo-NHS to increase reaction efficiency or to stabilize active intermediate for later reaction to amines
  • Neutral linkage: Forms neutral amide bonds between carboxyls and amines
  • Water-soluble Reagent: Add directly to reactions in aqueous, physiological buffers
  • Soluble reaction byproducts: Easily removed by washing with water or dilute acid
  • High-purity, crystalline reagent: Use to create high-quality, activated derivatives
Applications:
  • Conjugate carboxyl and amino groups among peptides and proteins
  • Couple haptens to immunogenic carrier proteins (e.g., attach a peptide to KLH)
  • Immobilize peptide antigens to affinity-purify antibodies
  • Create NHS-activated, amine-reactive labeling compounds
  • Crosslink proteins to carboxyl coated beads or surfaces
  • Activate nanoparticles with amine-reactive Sulfo-NHS esters
TRUSTED_SUSTAINABILITY
Specificatie

Specificatie

Amine-Carboxyl
EDC
No
Upon receipt store desiccated at -20°C.
Wet Ice
Chemical Labeling
Carbodiimide
Powder
Water
Yes
No
191.7
0.0 Å
No
No-Weigh™, Pierce™
Heterobifunctional
Short (<10 Å)
10 x 1 mg
Standard, Single-use, Premium-grade
Crosslinker
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Veiligheid en behandeling

Veiligheid en behandeling

Productidentificatie
  • Pierce EDC No-Weigh, 10 x 1 mg

Signaalwoord
  • Waarschuwing

Gevarencategorie
  • Ernstig oogletsel/oogirritatie Categorie 2
  • Huidcorrosie/-irritatie Indeling Categorie 2
  • Dzia anie toksyczne na narzady docelowe Categorie 3

Gevarenaanduiding
  • H315-Veroorzaakt huidirritatie.
  • H319-Veroorzaakt ernstige oogirritatie.
  • H335-Kan irritatie van de luchtwegen veroorzaken.

Veiligheidsmaatregel
  • P261-Inademing van stof/rook/gas/nevel/damp/spuitnevel vermijden.
  • P264-Na het werken met dit product grondig wassen.
  • P271-Alleen buiten of in een goed geventileerde ruimte gebruiken.
  • P280-Beschermende handschoenen/beschermende kleding/oog­bescherming/gelaatsbescherming dragen.
  • P302+P352-BIJ CONTACT MET DE HUID: met veel water/ wassen.
  • P304+P340-NA INADEMING: de persoon in de frisse lucht brengen en ervoor zorgen dat deze gemakkelijk kan ademen.
  • P305+P351+P338-BIJ CONTACT MET DE OGEN: voorzichtig afspoelen met water gedurende een aantal minuten; contactlenzen verwijderen, indien mogelijk; blijven spoelen.
  • P312-Bij onwel voelen een ANTIGIFCENTRUM/arts/ raadplegen.
  • P332+P313-Bij huidirritatie: een arts raadplegen.
  • P337+P313-Bij aanhoudende oogirritatie: een arts raadplegen.
  • P362+P364-Verontreinigde kleding uittrekken en wassen alvorens deze opnieuw te gebruiken.
  • P501b-Inhoud/verpakking afvoeren naar verwerken volgens de plaatselijke/regionale/nationale/internationale voorschriften.

Aanvullende informatie
  • MIXTURE LIST-Bevat: N-dimethyl-N-(ethylcarbonimidoyl)-N-1,3-propanediamine

SDS
Documentatie

Documentatie

Certificates
Speciale aanbiedingen

Speciale aanbiedingen

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