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Thermo Scientific™ pH Gradient Buffers
Robust reproducible gradients that are applicable to a wide range of MAbs and ready to use with existing LC columns and systems, without the need to formulate mobile phases.
Merk: Thermo Scientific™ 083275
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Beschrijving
Obtain fast and highly robust, reproducible HPLC gradients using Thermo Scientific™ CX-1 pH Gradient Buffers. Simple to optimize and easily automated, these buffers are applicable for HPLC separation of the majority of monoclonal antibody (mAb) biotherapeutics drugs. CX-1 pH Gradient Buffers are ready to use with existing HPLC columns without the need to formulate mobile phases. The CX-1 buffers save time in method development, facilitate method transfer to QA/QC for a wide range of mAb charge variants through a generic HPLC-based approach to mAb characterization, and do not require time-consuming mobile phase adjustments.
pH buffer solutions can be used to generate highly reproducible, linear pH gradients in cation exchange chromatography.
- Robust, reproducible gradients
- Predict biomolecule pH
- Simple method optimization
- Easily automated
- Applicable to the majority of MAbs
Unlike traditional cation exchange chromatography using salt gradients, it is possible to predict the pH and the expected retention of the charge variants and use a narrow pH range to get a higher resolution separation.
Specifications
| CX-1 pH Gradient Buffer B | |
| Thermo Scientific | |
| 125 mL | |
| 125 mL |
| LC Columns and Systems | |
| CX-1 pH Gradient Buffer B | |
| 10.2 |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- 125ML CX-1 pH Gradient Buffer B (pH 10.2)
Signal Word
- Waarschuwing
Hazard Category
- Ernstig oogletsel/oogirritatie Categorie 2
- Huidcorrosie/-irritatie Indeling Categorie 2
Hazard Statement
- H315-Veroorzaakt huidirritatie.
- H319-Veroorzaakt ernstige oogirritatie.
Precautionary Statement
- P264-Na het werken met dit product grondig wassen.
- P280-Beschermende handschoenen/beschermende kleding/oogbescherming/gelaatsbescherming dragen.
- P302+P352-BIJ CONTACT MET DE HUID: met veel water/ wassen.
- P305+P351+P338-BIJ CONTACT MET DE OGEN: voorzichtig afspoelen met water gedurende een aantal minuten; contactlenzen verwijderen, indien mogelijk; blijven spoelen.
- P332+P313-Bij huidirritatie: een arts raadplegen.
- P337+P313-Bij aanhoudende oogirritatie: een arts raadplegen.
Supplemental information
- MIXTURE LIST-Bevat: sodium hydroxide, chloroform
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