Thermo Scientific™ 5-fluor-orotisch zuur

Detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) dicarboxylase with Thermo Scientific™ 5-Fluoroorotic Acid, used in yeast molecular genetics.

Merk: Thermo Scientific™ R0811

73.84 EUR valid until 2025-04-18
Use promo code "24107" to get your promotional price.

Bekijk meerdere types van dit product via de

Produktcode. 10609920

104.00 / 1 gram

This item is not returnable. View return policy

Beschrijving

5-Fluoroorotic Acid is a yeast with an active URA3 gene (Ura+) converts 5-FOA to fluorodeoxyuridine, which is toxic to cells (see the scheme below). Yeast strains carrying a mutation in the URA3 gene grow in the presence of 5-FOA if the media is supplemented with uracil. 5-FOA is frequently used in experiments with Saccharomyces cerevisiae (URA3), Schizosaccharomyces pombe (URA4 and URA5), Candida albicans (URA3), and E. coli (pyrF).

Yeast with an active URA3 gene (Ura+) converts 5-FOA to fluorodeoxyuridine, which is toxic to cells (see the scheme below). Yeast strains carrying a mutation in the URA3 gene grow in the presence of 5-FOA if the media is supplemented with uracil. 5-FOA is frequently used in experiments with Saccharomyces cerevisiae (URA3), Schizosaccharomyces pombe (URA4 and URA5), Candida albicans (URA3) and E.coli (pyrF).

Recommended for:

Detection of URA3 gene expression in yeast; Construction of yeast 2-hybrid libraries (1); Other areas of yeast genetics including gene replacement, analysis of transposable genetic elements and identification of gene mutations.

Note:

Low solubility in water. Solubility in dimethylsulfoxide is greater than 150mg/mL. Preparation of a 100mg/mL solution in dime-thylsulfoxide is recommended.

Specificatie

Chemische naam of materiaal	5-Fluoroorotic Acid
Producttype	5-Fluoroorotic Acid
Aantal	1 g
Vorm	Powder

Product Suggestions Veiligheid en behandeling

Veiligheid en behandeling

Productidentificatie

5-Fluoroorotic acid monohydrate

Signaalwoord

Waarschuwing

Gevarencategorie

Acute toxiciteit Categorie 4
Ernstig oogletsel/oogirritatie Categorie 2
Huidcorrosie/-irritatie Indeling Categorie 2
Dzia anie toksyczne na narzady docelowe Categorie 3

Gevarenaanduiding

H302-Schadelijk bij inslikken.
H315-Veroorzaakt huidirritatie.
H319-Veroorzaakt ernstige oogirritatie.
H335-Kan irritatie van de luchtwegen veroorzaken.

Veiligheidsmaatregel

P280-Beschermende handschoenen/beschermende kleding/oogbescherming/gelaatsbescherming dragen.
P301+P330+P331-NA INSLIKKEN: de mond spoelen - GEEN braken opwekken.
P302+P352-BIJ CONTACT MET DE HUID: met veel water/ wassen.
P304+P340-NA INADEMING: de persoon in de frisse lucht brengen en ervoor zorgen dat deze gemakkelijk kan ademen.
P312-Bij onwel voelen een ANTIGIFCENTRUM/arts/ raadplegen.
P332+P313-Bij huidirritatie: een arts raadplegen.
P337+P313-Bij aanhoudende oogirritatie: een arts raadplegen.

Aanvullende informatie

MIXTURE LIST-Bevat: 5-Fluoroorotic acidmonohydrate

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

Your Name

Email Address *

Type of Issue *

Detailed Description of Issue/Request *

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.

For Research Use Only. Not for use in diagnostic procedures.

Spot an opportunity for improvement?Share a Content Correction

Thermo Scientific™ 5-fluor-orotisch zuur

Beschrijving

Specificatie

Product Suggestions

Veiligheid en behandeling

Documentatie

Speciale aanbiedingen