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  7. Doxorubicin Hydrochloride, Fisher BioReagents

Doxorubicin Hydrochloride, Fisher BioReagents

36.94 - 1340.00

Chemische identificatiekenmerken

CAS 25316-40-9
Moleculaire formule C27H30ClNO11
Molecular Weight (g/mol) 579.98
MDL-nummer MFCD00077757,MFCD00077757,MFCD00941448
InChI Key MWWSFMDVAYGXBV-FGBJBKNOSA-N
Synoniem doxorubicin hydrochloride, adriamycin, doxorubicin hcl, adriacin, adriblastina, rubex, adriamycin hydrochloride, adriblastin, adriamycin pfs
PubChem CID 129626538
IUPAC Name (7R,9R)-7-[(2S,4R,5R,6R)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride
SMILES [H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
Meer specificaties weergeven

Producten 4
Produktcode Merk Aantal Verpakking Prijs Hoeveelheid en beschikbaarheid  
Produktcode Merk Aantal Verpakking Prijs Hoeveelheid en beschikbaarheid  
10512955
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Fisher BioReagents
BP2516-1 		1 mg Amber Glass N/A N/A N/A
11413074
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Fisher BioReagents
BP2516-5 		5 mg Amber Glass N/A N/A N/A
10133293
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Fisher BioReagents
BP2516-10 		10 mg Amber Glass N/A N/A N/A
10767945
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Fisher BioReagents
BP2516-50 		50 mg Amber Glass N/A N/A N/A
Beschrijving

Beschrijving

Doxorubicin Hydrochloride

Doxorubicin HCL is a chemotherapeutic agent. Antitumor, immunosuppressive, and antibiotic agent. It blocks RNA polymerase and reverse transcriptase. Also inhibits nucleic acid synthesis.
Specificatie

Chemische identificatiekenmerken

25316-40-9
579.98
MWWSFMDVAYGXBV-FGBJBKNOSA-N
129626538
[H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
C27H30ClNO11
MFCD00077757,MFCD00077757,MFCD00941448
doxorubicin hydrochloride, adriamycin, doxorubicin hcl, adriacin, adriblastina, rubex, adriamycin hydrochloride, adriblastin, adriamycin pfs
(7R,9R)-7-[(2S,4R,5R,6R)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride

Specificatie

Doxorubicin Hydrochloride
216°C
Orange
C27H30ClNO11
15, 3487
Soluble in water
[H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
579.98
580
25316-40-9
216°C
(by HPLC): ≥95%
MFCD00077757,MFCD00077757,MFCD00941448
doxorubicin hydrochloride, adriamycin, doxorubicin hcl, adriacin, adriblastina, rubex, adriamycin hydrochloride, adriblastin, adriamycin pfs
MWWSFMDVAYGXBV-FGBJBKNOSA-N
(7R,9R)-7-[(2S,4R,5R,6R)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride
129626538
Powder or Solid
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Veiligheid en behandeling

Veiligheid en behandeling

WARNING!

Emergency Overview
May cause cancer. Risk of serious damage to eyes. Irritating to respiratory system and skin. May cause heritable genetic damage. Possible risk of impaired fertility. Possible risk of harm to the unborn child. Use personal protective equipment. Use only under a chemical fume hood. Wash off immediately with plenty of water for at least 15 minutes. Obtain medical attention. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required. Immediate medical attention is required. Move to fresh air.

NFPA

Health:2
Flammability:1
Instability:0

Recommended Storage : 2° to 8°C

Productidentificatie
  • Doxorubicin hydrochloride

Signaalwoord
  • Gevaar

Gevarencategorie
  • Acute toxiciteit Categorie 4
  • Kankerverwekkendheid Categorie 1B
  • Ernstig oogletsel/oogirritatie Categorie 1
  • Mutageniteit van geslachtscellen Categorie 1B
  • Giftigheid voor de voortplanting Categorie 2
  • Huidcorrosie/-irritatie Indeling Categorie 2
  • Dzia anie toksyczne na narzady docelowe Categorie 3

Gevarenaanduiding
  • H318-Veroorzaakt ernstig oogletsel.
  • H340-Kan genetische schade veroorzaken.
  • H350-Kan kanker veroorzaken.
  • H315-Veroorzaakt huidirritatie.
  • H361fd-Wordt ervan verdacht de vruchtbaarheid te schaden. Wordt ervan verdacht het ongeboren kind te schaden.
  • H335-Kan irritatie van de luchtwegen veroorzaken.
  • H302-Schadelijk bij inslikken.

Veiligheidsmaatregel
  • P201-Alvorens te gebruiken de speciale aanwijzingen raadplegen.
  • P280-Beschermende handschoenen/beschermende kleding/oog­bescherming/gelaatsbescherming dragen.
  • P303+P361+P353-BIJ CONTACT MET DE HUID (of het haar): verontreinigde kleding onmiddellijk uittrekken. Huid met water afspoelen/afdouchen.
  • P305+P351+P338-BIJ CONTACT MET DE OGEN: voorzichtig afspoelen met water gedurende een aantal minuten; contactlenzen verwijderen, indien mogelijk; blijven spoelen.
  • P310-Onmiddellijk een ANTIGIFCENTRUM/arts/ raadplegen.

SDS
Documentatie

Documentatie

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