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Dextran Sulfate Sodium Salt, Colitis Grade (36,000 to 50,000), MP Biomedicals™

Induces severe colitis (inflammatory bowel disease) in laboratory animals

Merk:  MP Biomedicals 0216011025

444.60 EUR valid until 2025-04-30
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Beschrijving

Beschrijving

Induces severe colitis (inflammatory bowel disease) in laboratory animals

Dextran sulfate sodium salt, or DSS, is a synthetic sulfated branched polysaccharide derivative of dextran that has multiple uses in biomedical and clinical research. One important property of DSS is to trigger colitis in mice and rats when administered in drinking water. DSS binds to medium-chain-length fatty acids in the colon and induces intestinal inflammation. Colitis-grade DSS (MW = 36,000 to 50,000) from MP Bio is one of the most widely used products based on peer reviewed scientific publications.

  • Induces severe colitis (inflammatory bowel disease)
  • Highest sulfur content – 19%
  • Highest chirality - +104° of specific rotation
  • Lowest pH – 6.2 at 1% solution
TRUSTED_SUSTAINABILITY
Specificatie

Specificatie

Dextran Sulfate Sodium Salt
5 to 7.11 (1% aqueous solution)
Powder
92°C
MFCD00081551
25 g
*-OC[C@H]1O[C@H](OC[C@H]2O[C@H](-*)[C@H](O[*])[C@@H](O[*])[C@@H]2O[*])[C@H](O[*])[C@@H](O-*)[C@@H]1O[*]
40,000
Colitis Grade
Plastic Container
White
9011-18-1
310°C
(C6H7O5)m(C6H7O5)n
Soluble in water
BLFLLBZGZJTVJG-UHFFFAOYSA-N
Dextran sulfate sodium salt
Used for inducing ulcerative colitis in animals and extensively to study colon cancer developing in relation to colonic inflammation
<10%
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