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Thermo Scientific Chemicals Colchicine, 97%

Colchicine, 7alphah-colchicine, CAS # 64-86-8, is a laboratory grade formulation of the anti-inflammatory plant alkaloid drug.

67.94 - 1448.21

Chemische identificatiekenmerken

CAS 64-86-8
Moleculaire formule C22H25NO6
Molecular Weight (g/mol) 399.44
MDL-nummer MFCD00078484,MFCD00078484
InChI Key IAKHMKGGTNLKSZ-INIZCTEOSA-N
Synoniem colchicine, colchicina, colchicin, condylon, colchicinum, colchisol, colsaloid, colcin, colchineos, 7alphah-colchicine
PubChem CID 45038708
IUPAC Name 2,2,2-trideuterio-N-[(7S)-1,2,3-trimethoxy-9-oxo-10-(trideuteriomethoxy)-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
SMILES COC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1
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Producten 4
Produktcode Merk Aantal Verpakking Prijs Hoeveelheid en beschikbaarheid  
Produktcode Merk Aantal Verpakking Prijs Hoeveelheid en beschikbaarheid  
10185230
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Thermo Scientific Chemicals
227125000 		500 mg Glass bottle
67.94
500 mg
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10388310
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Thermo Scientific Chemicals
227120010 		1 g Glass bottle
135.68
1 gram
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10174953
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Thermo Scientific Chemicals
227120050 		5 g Glass bottle
359.79
5 gram
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13428488
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Thermo Scientific Chemicals
227120250 		25 g Glass bottle
1448.21
25 gram
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Beschrijving

Beschrijving

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

  • Colchicine (7alphah-colchicine) is an alkaloid found in Colchicum autumnale that has been shown to have anti-gout and anti-inflammatory properties
  • Colchicine binds tubulin and prevents the migration of immune cells, reducing inflammation

Applications

  • Colchicine is an anti-mitotic; may be used in the study of cell proliferation and migration
  • Intended for in vivo and in vitro research applications
  • For research use only, not intended to treat disease
Specificatie

Chemische identificatiekenmerken

64-86-8
399.44
IAKHMKGGTNLKSZ-INIZCTEOSA-N
45038708
COC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1
C22H25NO6
MFCD00078484,MFCD00078484
colchicine, colchicina, colchicin, condylon, colchicinum, colchisol, colsaloid, colcin, colchineos, 7alphah-colchicine
2,2,2-trideuterio-N-[(7S)-1,2,3-trimethoxy-9-oxo-10-(trideuteriomethoxy)-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide

Specificatie

Colchicine
150.0°C to 160.0°C
Authentic
C22H25NO6
14,IV,946
− 250.00
Solubility in water: 45g/l (20°C). Other solubilities: soluble in alcohol and chloroform,practically insoluble in petroleum ether,1g/220mL ether,1g/100mL benzene
COC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1
399.44
399.44
Powder
64-86-8
Yellow
96% min. on anhydrous and solvent-free substance (HPLC)
MFCD00078484,MFCD00078484
15,2455
colchicine, colchicina, colchicin, condylon, colchicinum, colchisol, colsaloid, colcin, colchineos, 7alphah-colchicine
IAKHMKGGTNLKSZ-INIZCTEOSA-N
2,2,2-trideuterio-N-[(7S)-1,2,3-trimethoxy-9-oxo-10-(trideuteriomethoxy)-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
45038708
97%
Video's
Veiligheid en behandeling

Veiligheid en behandeling

GHS H Statement:
Fatal if swallowed.
May cause genetic defects.

GHS P Statement:
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
Obtain special instructions before use.
IF exposed or concerned: Get medical advice/attention.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

GHS Signal Word: Danger

missing translation for 'einecsNumber' : 200-598-5

Productidentificatie
  • Colchicine

Signaalwoord
  • Gevaar

Gevarencategorie
  • Acute toxiciteit Categorie 2
  • Mutageniteit van geslachtscellen Categorie 1B

Gevarenaanduiding
  • H340-Kan genetische schade veroorzaken.
  • H300-Dodelijk bij inslikken.

Veiligheidsmaatregel
  • P201-Alvorens te gebruiken de speciale aanwijzingen raadplegen.
  • P301+P310-NA INSLIKKEN: onmiddellijk een ANTIGIFCENTRUM/arts/ raadplegen.
  • P308+P313-NA (mogelijke) blootstelling: een arts raadplegen.

SDS
Documentatie

Documentatie

Product Certifications

RUO – Research Use Only

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