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  6. Thermo Scientific Chemicals Cefotaxime sodium salt, 95%

Thermo Scientific Chemicals Cefotaxime sodium salt, 95%

Cefotaxime sodium salt, CAS # 64485-93-4, is the sodium salt form of cefotaxime with β-lactamase resistant antibiotic activity.

58.14 - 569.92

Chemische identificatiekenmerken

CAS 64485-93-4
Moleculaire formule C16H16N5NaO7S2
Molecular Weight (g/mol) 477.44
MDL-nummer MFCD00079073
InChI Key AZZMGZXNTDTSME-JUZDKLSSSA-M
PubChem CID 88631411
SMILES [Na+].CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(C)=O)=C(N2C1=O)C([O-])=O)C1=CSC(N)=N1
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Produktcode Merk Aantal Verpakking Prijs Hoeveelheid en beschikbaarheid  
Produktcode Merk Aantal Verpakking Prijs Hoeveelheid en beschikbaarheid  
15219946
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Thermo Scientific Chemicals
454950010 		1 g Glass Bottle
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15229946
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Thermo Scientific Chemicals
454950050 		5 g Glass Bottle
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Thermo Scientific Chemicals
454950250 		25 g Glass Bottle N/A N/A N/A
Beschrijving

Beschrijving

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• The cefotaxime sodium salt is a - lactamase considered a third-generation cephalosporin with antibiotic and bactericidal activities
• This compound exerts its biological activity by binding to penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall leading to their inactivation. The inactivation of these proteins affects the cross-linking of peptidoglycan chains required for bacterial cell wall strength and rigidity, resulting in the weakening of cell walls and cell lysis.

Applications

• It is an efficient antibacterial compound that acts against gram-negative bacteria, without activity against gram-positive bacteria such as pseudomonas and penicillin-resistant strains of streptococcus pneumonia
• It has been used for plant cell culture and human cell lines in vitro
• Cefotaxime sodium salt has been used in antibiotic susceptibility testing (AST) methods
• Cefotaxime sodium salt is also used to remove bacteria from Ostreococcus tauri cultures

Specificatie

Chemische identificatiekenmerken

64485-93-4
477.44
AZZMGZXNTDTSME-JUZDKLSSSA-M
[Na+].CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(C)=O)=C(N2C1=O)C([O-])=O)C1=CSC(N)=N1
C16H16N5NaO7S2
MFCD00079073
88631411

Specificatie

Cefotaxime sodium salt
64485-93-4
95%
MFCD00079073
AZZMGZXNTDTSME-JUZDKLSSSA-M
sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
88631411
95%
Cefotaxime Sodium Salt
201.0°C to 210.0°C
C16H16N5NaO7S2
Solubility in water: soluble.
[Na+].CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(C)=O)=C(N2C1=O)C([O-])=O)C1=CSC(N)=N1
477.44
477.44
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Veiligheid en behandeling

Veiligheid en behandeling

Productidentificatie
  • Cefotaxime sodium salt

Signaalwoord
  • Gevaar

Gevarencategorie
  • Ernstig oogletsel/oogirritatie Categorie 2
  • Sensibilisatie van de luchtwegen Categorie 1
  • Huidcorrosie/-irritatie Indeling Categorie 2
  • Sensibilisering van de huid Categorie 1
  • Dzia anie toksyczne na narzady docelowe Categorie 3

Gevarenaanduiding
  • H317-Kan een allergische huidreactie veroorzaken.
  • H334-Kan bij inademing allergie- of astmasymptomen of ademhalingsmoeilijkheden veroorzaken.
  • H319-Veroorzaakt ernstige oogirritatie.
  • H335-Kan irritatie van de luchtwegen veroorzaken.
  • H315-Veroorzaakt huidirritatie.

Veiligheidsmaatregel
  • P280-Beschermende handschoenen/beschermende kleding/oog­bescherming/gelaatsbescherming dragen.
  • P302+P352-BIJ CONTACT MET DE HUID: met veel water/ wassen.
  • P304+P340-NA INADEMING: de persoon in de frisse lucht brengen en ervoor zorgen dat deze gemakkelijk kan ademen.
  • P305+P351+P338-BIJ CONTACT MET DE OGEN: voorzichtig afspoelen met water gedurende een aantal minuten; contactlenzen verwijderen, indien mogelijk; blijven spoelen.
  • P312-Bij onwel voelen een ANTIGIFCENTRUM/arts/ raadplegen.

SDS
Documentatie

Documentatie

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RUO – Research Use Only

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