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BD Pharmingen™ IHC Zinc Fixative

An alternative to formalin fixation of tissue for paraffin embedded sections

Merk:  BD 552658


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Produktcode. 15886838

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Beschrijving

Beschrijving

Ten percent neutral buffered formalin fixes tissue by cross-linking proteins, potentially causing a conformational change or “masking” of the antigenic epitope and leading to reduced or absent antibody reactivity. Different antigen retrieval techniques are used to unmask the epitope; however, many times it is not possible to retrieve the epitope and get optimal immunohistochemical staining. In these situations the use of IHC Zinc fixative, which is a milder fixative than formalin, is recommended.

  • Zinc-fixed paraffin embedded sections show very good immunostaining with many leukocytes markers and depict tissue morphology comparable to formalin-fixation
  • Use of antigen retrieval techniques on the zinc-fixed paraffin sections may further enhance the antibody reactivity in some cases

There are a few antigens that are not preserved by zinc-fixation. In these situations use of fresh frozen tissue for immunohistochemical staining is the only alternative.

TRUSTED_SUSTAINABILITY
Specificatie

Specificatie

100°C
Room temperature
Fixative
Immunohistochemical staining
Liquid
Clear
10 X
500mL
7.2
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Veiligheid en behandeling

Veiligheid en behandeling

Productidentificatie
  • 10X Zinc Fixative (Formalin Free)

Signaalwoord
  • Gevaar

Gevarencategorie
  • AQUATISCH GEVAAR OP LANGE TERMIJN Categorie 2 voor chronische toxiciteit
  • Ernstig oogletsel/oogirritatie Categorie 1
  • Huidcorrosie/-irritatie Indeling Categorie 2

Gevarenaanduiding
  • H315-Veroorzaakt huidirritatie.
  • H318-Veroorzaakt ernstig oogletsel.
  • H411-Giftig voor in het water levende organismen, met langdurige gevolgen.

Veiligheidsmaatregel
  • P280-Beschermende handschoenen/beschermende kleding/oog­bescherming/gelaatsbescherming dragen.
  • P302+P352-BIJ CONTACT MET DE HUID: met veel water/ wassen.
  • P305+P351+P338-BIJ CONTACT MET DE OGEN: voorzichtig afspoelen met water gedurende een aantal minuten; contactlenzen verwijderen, indien mogelijk; blijven spoelen.
  • P501b-Inhoud/verpakking afvoeren naar verwerken volgens de plaatselijke/regionale/nationale/internationale voorschriften.

Aanvullende informatie
  • MIXTURE LIST-Bevat: zinc acetate, zinc chloride

SDS
Documentatie

Documentatie

Certificates
Speciale aanbiedingen

Speciale aanbiedingen

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