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Thermo Scientific Chemicals 5-Fluorouracil, 99%
5-Fluorouracil, CAS # 51-21-8, is an analogue base composed of uracil with a position 5 hydrogen fluorine substitution.
28.74 - 863.00
Chemische identificatiekenmerken
| CAS | 51-21-8 |
|---|---|
| Moleculaire formule | C4H3FN2O2 |
| Molecular Weight (g/mol) | 130.08 |
| MDL-nummer | MFCD00006018 |
| InChI Key | GHASVSINZRGABV-UHFFFAOYSA-N |
| Synoniem | 5-fluorouracil, fluorouracil, 5-fu, fluoroplex, adrucil, efudex, carac, fluracil, fluoroblastin, kecimeton |
| PubChem CID | 3385 |
| ChEBI | CHEBI:46345 |
| IUPAC Name | 5-fluoro-1H-pyrimidine-2,4-dione |
| SMILES | FC1=CNC(=O)NC1=O |
| Produktcode | Merk | Aantal | Verpakking | Prijs | Hoeveelheid en beschikbaarheid | ||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Merk | Aantal | Verpakking | Prijs | Hoeveelheid en beschikbaarheid | ||||
|
10348170
|
Thermo Scientific Chemicals
228440010 |
1 g | Glass bottle |
28.74
1 gram |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
10697552
|
Thermo Scientific Chemicals
228440050 |
5 g | Glass bottle |
87.64
5 gram |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
11906531
|
Thermo Scientific Chemicals
228440250 |
25 g | Glass bottle |
283.41
25 gram |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
15159263
|
Thermo Scientific Chemicals
228441000 |
100 g | Glass bottle | N/A | |||||
Beschrijving
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• 5-Fluorouracil is an antimetabolite and antineoplastic that prevents DNA synthesis by blocking conversion of deoxyuridylic acid
• 5-Fluorouracil can replace uracil in RNA and prevent protein synthesis and cell growth
Applications
• 5-Fluorouracil can be used for laboratory research on tumor growth and immunosuppression
• 5-Fluorouracil may also be appropriate for laboratory studies of neurotoxicity, cell lysis, and DNA damage
Chemische identificatiekenmerken
| 51-21-8 | |
| 130.08 | |
| GHASVSINZRGABV-UHFFFAOYSA-N | |
| 3385 | |
| 5-fluoro-1H-pyrimidine-2,4-dione |
| C4H3FN2O2 | |
| MFCD00006018 | |
| 5-fluorouracil, fluorouracil, 5-fu, fluoroplex, adrucil, efudex, carac, fluracil, fluoroblastin, kecimeton | |
| CHEBI:46345 | |
| FC1=CNC(=O)NC1=O |
Specificatie
| 5-Fluorouracil | |
| 278.0°C to 282.0°C | |
| 190.0°C to 200.0°C (0.1 mmHg) | |
| Authentic | |
| C4H3FN2O2 | |
| 24,IV,1229 | |
| 5-fluorouracil, fluorouracil, 5-fu, fluoroplex, adrucil, efudex, carac, fluracil, fluoroblastin, kecimeton | |
| GHASVSINZRGABV-UHFFFAOYSA-N | |
| 5-fluoro-1H-pyrimidine-2,4-dione | |
| 3385 | |
| 130.08 | |
| Crystalline Powder |
| 51-21-8 | |
| White | |
| 0.5% (80°C, 4 hrs) (in vacuum) max. | |
| 99% | |
| MFCD00006018 | |
| 15,4213 | |
| Solubility in water: 12.2g/L (20°C). Other solubilities: 2.9g/L (20°C) in ethanol,readily soluble in aqueous alkali solutions,soluble in dmso | |
| FC1=CNC(=O)NC1=O | |
| 130.08 | |
| CHEBI:46345 | |
| 99% |
Safety and Handling
GHS H Statement
Suspected of causing genetic defects.
Suspected of damaging the unborn child.
Toxic if swallowed.
Harmful in contact with skin.
Harmful if inhaled.
Causes serious eye irritation.
Causes skin irri
GHS P Statement
Wear protective gloves/protective clothing/eye protection/face protection.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF INHALED: Remove victim to fresh air and keep at rest in a position comforta
GHS Signal Word: Danger
missing translation for 'einecsNumber' : 200-085-6
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
- 5-Fluorouracil
Signal Word
- Gevaar
Hazard Category
- Acute toxiciteit Categorie 3
- Acute toxiciteit Categorie 4
- Ernstig oogletsel/oogirritatie Categorie 2
- Mutageniteit van geslachtscellen Categorie 2
- Giftigheid voor de voortplanting Categorie 2
- Huidcorrosie/-irritatie Indeling Categorie 2
- Dzia anie toksyczne na narzady docelowe Categorie 3
Hazard Statement
- H315-Veroorzaakt huidirritatie.
- H319-Veroorzaakt ernstige oogirritatie.
- H341-Verdacht van het veroorzaken van genetische schade.
- H361d-Wordt ervan verdacht het ongeboren kind te schaden.
- H335-Kan irritatie van de luchtwegen veroorzaken.
- H312-Schadelijk bij contact met de huid.
- H332-Schadelijk bij inademing.
- H301-Giftig bij inslikken.
Precautionary Statement
- P280-Beschermende handschoenen/beschermende kleding/oogbescherming/gelaatsbescherming dragen.
- P301+P310-NA INSLIKKEN: onmiddellijk een ANTIGIFCENTRUM/arts/ raadplegen.
- P302+P352-BIJ CONTACT MET DE HUID: met veel water/ wassen.
- P304+P340-NA INADEMING: de persoon in de frisse lucht brengen en ervoor zorgen dat deze gemakkelijk kan ademen.
- P312-Bij onwel voelen een ANTIGIFCENTRUM/arts/ raadplegen.
- P337+P313-Bij aanhoudende oogirritatie: een arts raadplegen.
RUO – Research Use Only
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